This site is intended for health professionals only

Published on 6 February 2007

Share this story:

Dependency risks with tramadol


Tramadol withdrawal reactions may be a bigger problem than previously thought, the Swedish Medical Products Agency has announced. The Swedish adverse reactions database (SWEDIS) contains 71 reports of abstinence/withdrawal symptoms with tramadol (a drug that is prescribed for moderate to severe pain), 25 of which were also classed as dependence, habituation or increased tolerance. Treatment duration ranged from one week to more than three years, at dosages of 50–2,999mg, showing that withdrawal symptoms have been reported in low/normal doses, and after treatment periods of less than six months.

Most read

Latest Issue

Be in the know
Subscribe to Hospital Pharmacy Europe newsletter and magazine
Share this story: