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The All Wales Medicines Strategy Group (AWMSG) has extended recommendations for the use of an HIV drug.
Isentress (raltegravir; Merck, Sharpe & Dohme) can now be used by those who cannot take these types of medicines due to drug-drug interactions (PDF, 190k) or in combination with other antiretroviral medicines, for the treatment of HIV-1 infection in any adults who are resistant to or intolerant of non-nucleoside reverse transcriptase inhibitors or protease inhibitors.
However, the recommendations made by the AWMSG in 2008 for the use of the drug in treatment-experienced adults still applies.
The AWMSG has ruled that the prescribing of Revatio should be restricted to a doctor experienced in treating this condition in association with a National Commissioning Group-designated expert centre.
Also recommended for use within its current licensed indication to improve the exercise capacity of patients with pulmonary arterial hypertension (PDF, 150K), is hypertension drug Revatio (sildenafil; Pfizer).
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