Novosis AG has installed an integrated Doyen Medipharm Transdermal Device Converting and Packaging line at its facilities in Miesbach, Germany.
The new system optimises the development and production of a variety of transdermal devices, as it is adaptable to manufacture products in different shapes and sizes with a minimum of downtime at changeover.
A customised process efficiently minimises ladder waste of the drug. Automatic registration optimises the cut position, decreasing the number of patches rejected by the integrated quality control station.
The system uses Doyenâ€™s proven Transdermal Device Manufacturing and Four Side Seal Packaging technologies, converting up to 25 metres of PET/PE per minute. The transdermal patches are fed automatically onto Doyenâ€™s 4SS-400 four-side seal pouching machine to be hermetically sealed into peelable packs. An integrated quality control system detects and rejects splice, empty pouches and misplaced products.
Hubert Kaffl, process development spokesman at Novosis, sees the new system as an important addition in the product development process: â€œDoyen has provided us with a production line that is flexible enough to run tests on a varied range of transdermal devices. We are very impressed with the versatility and efficiency of the machine.
â€œI am delighted to say that we have recently placed an order for a second machine.â€