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Stem cells used on blocked arteries


Research into the use of stem cells for treating diseases caused by the obstruction of large arteries in the arms and legs has produced positive results.

Peripheral arterial disease (PAD) affects around one in 20 people over the age of 55 and is associated with conditions such as diabetes, obesity and stroke.

Work on mice by British adult stem cell firm ReNeuron found the animals were able to recover significant amounts of blood flow to affected limbs.

Chief scientific officer John Sinden said: “This work will give us a significant advantage as we look to move this cell line forward to the clinic as a non patient-specific therapeutic candidate for peripheral arterial disease.”

Stem cells can be used to create a variety of different cells in the body. When applied in the right conditions, it is hoped the cells can help repair damaged tissue.

ReNeuron is to begin human trials for stroke treatment in January after attaining UK approval. The condition, along with PAD and retinal diseases, are key targets for the company’s research.

Copyright Press Association 2009


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