This site is intended for health professionals only

UCB and Biogen Idec discontinue phase II clinical trial of CDP323

teaser

UCB and Biogen Idec announced today the discontinuation of the phase II clinical trial of CDP323 for the treatment of relapsing multiple sclerosis (MS).

Preliminary interim efficacy analysis showed that patients enrolled in this clinical trial did not benefit as expected from CDP323 compared to placebo after a six month treatment period. No cases of PML (progressive multifocal leukoencephalopathy) were noted.

Article continues below this sponsored advert
Featured Image
Explore the latest advances in cardiovascular care delivered by renowned experts from recognised Centres of Excellence and other NHS trusts around the UK. Gain CPD, put your burning questions to the experts, and boost your confidence when it comes to care for your patients.
Advertisement

CDP323 is an oral small molecule alpha4 integrin inhibitor that was being developed by UCB and Biogen Idec for relapsing forms of multiple sclerosis.

For UCB, results of this interim analysis trigger a re-valuation of the intangible asset “CDP323”. UCB expects a non-cash, non-recurring impairment of a high double-digit million pre-tax euro amount. This will be more than compensated by cash, non-recurring capital gains, which resulted from the divestitures UCB made earlier this year. More information on the financial impacts of both the impairment and the capital gains will be included in the Half Year Report 2009 of UCB, due July 31, 2009.

UCB






Be in the know
Subscribe to Hospital Pharmacy Europe newsletter and magazine

x