--> jQuery(window).scroll(function() { checkStick(); }); var mbannerid = '#div-gpt-ad-1563273235586-0'; var mfooterid = '#footermobilebanner'; var dfooterid = '#div-gpt-ad-1563274691467-0'; // Desktop sticky check function checkStick() { var launched = false; if (jQuery(window).height() > 500) { if (!jQuery('#dfp_stickyfooter').hasClass("closed")) { if (jQuery('#dfp_stickyfooter > div').length) { if (!jQuery('#dfp_stickyfooter > div').hasClass("cog-mb-sticky")) { var width = jQuery('#dfp_stickyfooter > div > iframe').width(); var height = jQuery('#dfp_stickyfooter > div > iframe').height(); if (parseInt(width) > 0) { launched = true; jQuery('#dfp_stickyfooter').attr('style', 'height: '+(height+30)+'px;').addClass('opened'); jQuery('#dfp_stickyfooter').append(' '); jQuery('#dfp_stickyfooter > div').addClass('cog-mb-sticky floating footer'); jQuery('#dfp_stickyfooter > div').attr('style', 'position:absolute; bottom:0;'); jQuery('#dfp_stickyfooter svg.close').on('click', function() { jQuery(this).parent().removeClass('opened').addClass('closed'); }); } } } } } if (!launched) { // Ad not ready yet window.setTimeout(checkStick, 250); } } jQuery(document).ready(function() {checkStick();}); -->

This site is intended for health professionals only

Drug “rivals nets” in malaria fight

teaser

A malaria drug treatment may be almost as effective as bug-deadly mosquito nets in preventing the disease in less prevalent areas, according to a study.

Experts from the London School of Hygiene & Tropical Medicine used mathematical modelling to predict the outcome of using artemisinin combination therapies (ACTs) as a first-line treatment for uncomplicated malaria.

The study, published in the journal PLoS Medicine, estimated the effects of ACT from clinical trial data. It showed that in low-transmission areas, a 53% decrease in clinical episodes would occur if all current treatments were switched to ACT – in line with figures relating to the effectiveness of insecticide-treated nets (ITNs). This compared to 21% in the areas with the highest transmission.

In high transmission areas, long-acting antimalarial regimens may be needed to achieve significant transmission reductions, the study said.

Lead author Lucy Okell, of the London School of Hygiene & Tropical Medicine, said: “Overall, we predict that at existing treatment rates, a 100% switch to ACT from nonartemisinin drugs could reduce the rate of clinical episodes of malaria by between 21% and 53% if a short-acting ACT such as artemether-lumefantrine was used.

“As endemic countries gear up for malaria eradication, a target called for by the Bill and Melinda Gates Foundation in 2007, it will be important to know how choice of first-line treatment can help reach this goal’.”

Copyright Press Association 2008

PLoS Medicine

Be in the know
Subscribe to Hospital Pharmacy Europe newsletter and magazine

x