This site is intended for health professionals only

Study looks at effects of insulin


Diabetics can control high blood sugar levels after meals more effectively with a certain type of altered insulin, according to a study.

Pre-mixed insulin analogues – a modified form of conventional pre-mixed human insulin – are more effective than long-acting forms for patients with type 2 diabetes, a report funded by the Agency for Healthcare Research and Quality (AHRQ) found.

However, the Johns Hopkins University research shows conventional pre-mixed human insulin appears to be equally effective as pre-mixed insulin analogues for lowering blood sugar levels when patients go eight or more hours without eating.

Diabetes can cause serious problems with the heart, kidneys, eyes and nerves. Many patients with type 2 diabetes control their blood sugar through diet and use of oral medications. Recent research suggests that good blood glucose control can reduce loss of sight, kidney failure, and heart disease.

AHRQ director Dr Carolyn Clancy said: “While it is clear that pre-mixed insulin analogues offer certain advantages to patients with diabetes, what is good for one patient may not be good for another.

“This report offers an important reminder that patients with diabetes should review their treatment plans carefully with their physician.”

Copyright PA Business 2008


Be in the know
Subscribe to Hospital Pharmacy Europe newsletter and magazine